|Place of Origin:||shanxi|
|Model Number:||Male Enhancement Powder|
Payment & Shipping Terms:
|Minimum Order Quantity:||1g|
|Packaging Details:||Foil Bag, Cardboard Drum|
|Delivery Time:||Within 24 hours after payment|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram|
|Type:||Herbal Extract, Herbal Supplements, Maca Root And Tubers Powder, Herbal Powder, Maca Extract||Form:||Powder|
|Specification:||98% 99%, 10% 15%, 10%-80%, Straight Powder, 10%-98% Epimedium Extract||Storage:||Cool Dry Place, Light And Oxygen Resistant Containers, Preserve In Tightly Sealed|
|Color:||Yellowish Brown Fine Powder, Request, Light-yellow Fine Powder, Brown Yellow Powder, Red-brown To White Crystal||Name:||Tadalafil|
Male Enhancement Powder Tadalafil Treatment of erectile dysfunction in men.
Tadalafil (Tadalafil, Tadalafil) has a molecular formula of C22H19N3O4 and a molecular weight of 389.4. It has been widely used in the treatment of male erectile dysfunction since 2003, with the trade name Cialis (Cialis). In 2008, Eli Lilly and Company of the United States sold the commercial development rights of this product for the treatment of PAH to United Therapeutics. In June 2009, the FDA approved tadalafil in the United States for the treatment of patients with pulmonary arterial hypertension (PAH) under the trade name Adcirca. Tadalafil was introduced as a drug for the treatment of ED in 2003, and it takes effect 30 minutes after administration, but its best effect is 2h after the onset of action, and the effect can last for 36h, and its effect is not affected by food. Tadalafil is administered at a dose of 10 or 20 mg. The recommended initial dose is 10 mg. The dose is adjusted according to the patient's response and adverse reactions. Pre-market research shows that after 12 weeks of oral administration of 10 or 20 mg of tadalafil, the effective rates are 67% and 81%, respectively. Many studies have shown that tadalafil has a good effect in the treatment of ED.
Erectile Dysfunction: Tadalafil is a selective phosphodiesterase type 5 (PDE5) like sildenafil, but its structure is different from the latter, and a high-fat diet does not interfere with its absorption. Under the action of sexual stimulation, nitric oxide synthase (NOS) in penile nerve endings and vascular endothelial cells catalyzes the synthesis of nitric oxide (NO) from the substrate L-arginine. NO activates guanylate cyclase, which converts guanosine triphosphate to cyclic guanosine monophosphate (cGMP), thereby activating cyclic guanosine monophosphate-dependent protein kinase, resulting in a decrease in the concentration of calcium ions in smooth muscle cells, causing corpus cavernosum Erection occurs due to relaxation of smooth muscle. Phosphodiesterase type 5 (PDE5) degrades cGMP into inactive products, making the penis into a weak state. Tadalafil inhibits the degradation of PDE5, leading to the accumulation of cGMP, which relaxes the smooth muscle of the corpus cavernosum, leading to penile erection. Since nitrates are NO donors, combined use with tadalafil will significantly increase the level of cGMP and lead to severe hypotension. Therefore, the combined use of the two is contraindicated in clinical practice.
|Characters||Kind of white solid powder.|
Dosage of Tadalafil
1. For adult men: The recommended dose of this product is 10 mg, which is taken before sexual activity and is not affected by eating. If the effect of taking 10mg is not significant, you can take 20mg. Can be taken at least 30 minutes before sex. The maximum frequency of dosing is once a day. It is best not to take tadalafil daily on a continuous basis, as the safety of long-term use has not been established. At the same time, because the effects of tadalafil often last more than a day.
2. For elderly men: the elderly do not need to adjust the dose.
3. For men with renal insufficiency: No dose adjustment is required for patients with mild to moderate renal insufficiency. For patients with severe renal insufficiency, the maximum recommended dose is 10 mg. (See [Pharmacokinetics] for details.)
4. For men with hepatic insufficiency: The recommended dose of this product is 10 mg, which is taken before sexual activity and is not affected by food. There is limited information on the clinical safety of tadalafil in patients with severe hepatic impairment (Child-Pugh class C); if prescribing in such patients, a careful benefit/risk assessment of each patient is required by the prescribing physician. There are no data on doses higher than 10 mg in patients with hepatic insufficiency. (See [Precautions] and [Pharmacokinetics] for details.)
5. Men with diabetes: No dosage adjustment is required for diabetic patients.
6. For children and adolescents: Those under the age of 18 should not take this product.
Question 1 , How do you pack the order ?
Discreet package , the packing suits you best would be choosen to cross customs safely
Question 2 , What is your shipping method ?
Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail
Question 3 , if my order seized by custom ,what do you do ?
Resending police if the tracking number do not update online or it sezied by custom
Questions 4 , What is your payment accept ?
Safe and fast payment :Western Union ,Money Gram ,T/T ,Bitcoin
Questions 5 , Will you supply tracking number ?
Yes ,we supply tracking number for following .In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days
Question 6 , How many days will it take to my country after I do the payment ?
In general ,fastest with 3-5 business , slowest 5-7 business days
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