|Place of Origin:||shanxi|
|Model Number:||Male Enhancement Powder|
Payment & Shipping Terms:
|Minimum Order Quantity:||1g|
|Packaging Details:||Foil Bag, Cardboard Drum|
|Payment Terms:||L/C, D/A, D/P, T/T, Western Union, MoneyGram|
|Type:||Herbal Extract, Herbal Supplements, Maca Root And Tubers Powder, Herbal Powder, Maca Extract||Shelf Life:||Herbal Extract, Herbal Supplements, Maca Root And Tubers Powder, Herbal Powder, Maca Extract|
|Test Method:||TLC, HPLC, UV||Specification:||98% 99%, 10% 15%, 10%-80%, Straight Powder, 10%-98% Epimedium Extract|
|Storage:||Yellowish Brown Fine Powder, Request, Light-yellow Fine Powder, Brown Yellow Powder, Red-brown To White Crystal||Color:||Yellowish Brown Fine Powder, Request, Light-yellow Fine Powder, Brown Yellow Powder, Red-brown To White Crystal|
|Dosage Form:||Powder, Capsules|
Male Enhancement Powder Avanafil New drug for erectile dysfunction
Avanafil is a phosphodiesterase-5 inhibitor that increases blood flow to the penis. Like other drugs in its class (such as sildenafil, commonly known as "Viagra"), it should not be used in men who are also taking nitrates for chest pain, which may cause a sharp drop in blood pressure.
Indications: Treatment of erectile dysfunction.
Dosage: For most patients, take as needed about 15 minutes before sexual activity for rapid onset of action.
Pharmacokinetics: The peak response of Avanafil is 15-40 minutes after dosing, and the duration of the peak response is similar to that of sildenafil. Avanafil works faster than sildenafil and has few side effects.
Avanafil has a short onset of action and low side effects. The efficacy of the product can be maintained for 6 hours, and it can be completely excreted within 10 hours, which is very safe.
|Element||The main ingredient is Avanafil|
|Indications||Treatment of erectile dysfunction in men|
|Dosage||1. Adults take 100 mg orally once, once a day.
2. It can be adjusted to 50mg or 200mg according to tolerance. The lowest effective dose should be used.
3. Combination with moderate-acting CYP3A4 inhibitors and α-receptor antagonists, no more than 50 mg per day. Combination with strong CYP3A inhibitors is prohibited.
|Precautions||1. This product should not be used in combination with nitrates, as it can lead to hypotension, dizziness, syncope, heart attack or stroke.
2. Sexual activity can increase the risk of cardiovascular disease, and those with cardiovascular disease should pay attention.
3. If the penis is erected for more than 4 hours, with or without pain, you should seek medical attention.
4. If vision or hearing loss occurs during the use of this product, you should seek medical attention immediately.
How to use Avanafil?
Patients should take it orally once a day according to the actual situation, and the recommended dosage should be halved for the first use. If the effect is not satisfactory, the dosage can be gradually increased. Can be taken with or without food. It is recommended that patients take it about 30 minutes before a specific exercise, and some male patients may arouse in about 15 minutes, so it can even be taken 15 minutes before a specific exercise.
During sexual stimulation, the penis becomes erect due to increased blood flow to the penis due to relaxation of the penile arteries and smooth muscle of the corpus cavernosum. This response is mediated by nitric oxide (NO) released from nerve endings and endothelial cells. NO stimulates smooth muscle cells to synthesize cyclic guanosine monophosphate (cGMP). cGMP causes smooth muscle relaxation and increases blood flow to the cavernosal body. Avanafil enhances erectile function by inhibiting phosphodiesterase 5 (PDE5), which increases cGMP. Avanafil has no direct relaxation effect on isolated human cavernosal smooth muscle. Although it can enhance the effect of NO by inhibiting PDE5, the release of local NO requires sexual stimulation, so PDE5 inhibitor does not work in the absence of sexual stimulation. In vitro test results show that avanafil is selective for PDE5. Its effect on PDE5 is much stronger than that of other known phosphodiesterase types (100-fold stronger than PDE6, 1,000-fold stronger than PDE4, PDE8 and PDE10, 5,000-fold stronger than PDE2 and PDE7, 10,000-fold for PDE1, PDE3, PDE9, and PDE11). The effect of avanafil on PDE5 is 100 times stronger than that on PDE6. PDE6 mainly exists in the retina and is related to light transmission. In addition to human cavernosal smooth muscle, PDE5 is also present in other tissues, including platelets, blood vessels, visceral smooth muscle, skeletal muscle, brain, heart, liver, kidney, lung, pancreas, prostate, bladder, testis, and seminal vesicles. Inhibition of PDE5 in these tissues by avanafil may be the basis for NO's enhanced antiplatelet aggregation in vitro and peripheral vascular expansion in vivo.
Question 1 , How do you pack the order ?
Discreet package , the packing suits you best would be choosen to cross customs safely
Question 2 , What is your shipping method ?
Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail
Question 3 , if my order seized by custom ,what do you do ?
Resending police if the tracking number do not update online or it sezied by custom
Questions 4 , What is your payment accept ?
Safe and fast payment :Western Union ,Money Gram ,T/T ,Bitcoin
Questions 5 , Will you supply tracking number ?
Yes ,we supply tracking number for following .In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days
Question 6 , How many days will it take to my country after I do the payment ?
In general ,fastest with 3-5 business , slowest 5-7 business days
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