Product Description

ISO Certified GW501516 99%min HPLC

Raw Powder CAS 317318 70 0
Detail:
Product Name:Endurobol,GW501516,Cardarine
Alias:GSK-516,GW-501516
CAS NO.:317318-70-0
Molecular Formula:C21H18F3NO3S2
Molecular Weight:453.50
Purity:99%

GW501516 (Cardarine) is a drug that acts as a PPARd modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies.
GW501516 was discovered as a result of GSK and Ligand Pharma research collaborations that started in the early 1990’s. Interestingly, the compound reached phase 1 trials in 2000 for treatment of lipid strain, and then, it was discontinued in 2008. Nonetheless, today, it is used as a research compound, whilst athletes use it for performance enhancing and fat burning purposes.

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Medical Use
Cardarine was primarily developed to treat obesity, diabetes, lipid strain, and heart health problems. As a matter of fact, those who run blood work will notice that cardarine will magically aid with lipid strain, and their cholesterol levels will improve substantially.

Athletic Use
Endurance athletes may increase exercise endurance by stacking this PPAR with the AMP analog drug AICAR, or run cardarine solo. As a result, they will have a greater ability to reach higher RPM’s during their runs without hitting the maximum heart rate. Regarding the bodybuilders, cardarine can benefi

them in two ways:
1. Its ability to burn fat
2. Its ability to help the athlete have harder and longer workouts, without getting winded.

harder and longer workouts, without getting winded.

Fat Loss

In terms of obesity, cardarine reverses metabolic abnormalities in obese and pre-diabetic men by stimulating fatty acid oxidation. That is, it burns fat by increasing glucose uptake in skeletal muscle tissue, which changes the body’s metabolism to burn fat for energy instead of muscle or carbs. Incredibly, it does all this without dropping blood sugar levels like diabetic drugs do. Interestingly, when mice were given a high fat diet, they still lost fat, which proves that cardarine prevents obesity.

Functions
It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 could be used by athletes as an ergogenic performance enhancing drug.The most common use of GW consists of the extreme amount of endurance and recovery increase. The other main use of GW-501516 is to aid in fat loss. GW-501516 has shown to melt away fat at a rapid pace.
GW501516 is a PPARo receptor.
It activates the same pathways activated through exercise, including PPARo and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound alone.