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Product Details:
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| Place of Origin: | shaanxi |
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| Brand Name: | xn |
| Certification: | GMP,SGS,BV,ISO |
| Model Number: | aicar |
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Payment & Shipping Terms:
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| Minimum Order Quantity: | 1g |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag, carton or more according to customer requirements |
| Delivery Time: | Within 24 hours after payment |
| Payment Terms: | T/T, Western Union, MoneyGram,bitcoin |
| Supply Ability: | 3000kg/month |
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Detail Information |
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| Name: | Aicar | Place Of Origin: | China |
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| Purity: | 99.5% | Usage: | Bodybuilding&athletes Competition |
| Molecular Formula: | C27H36N4O5S.CH4O3S | Cas: | 2627-69-2 |
| Character: | White Powder | MW: | 624.776 |
| High Light: | Raw Powder Aicar SARMs SGS,aicar powder SGS,C27H36N4O5S.CH4O3S Aicar SARMs |
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Product Description
Sarms Raw Powder SARM Raw Powder 99% High Purity AICAR Powder ACADESINE Powder CAS: 2627-69-2
Description
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.
Commerce Clause
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Dosage
Dosages range from 150 milligrams (mg) per day (if stacked with GW), up to 500mg a day when used solo. Considering the fact that each bottle typically comes in 50mg dosages, that is quite expensive, as already mentioned above. Economically, it makes most sense to run AICAR during the 4 weeks leading up to your competition.
Related SARMs and Usage:
| name | Usage |
| AICAR | acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown |
| MK2866 | medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy. |
| MK-677 | A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly |
| LGD-4033 | pharmacological profile similar to that of enobosarm, Ostarine,MK-2866 |
| GW1516 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
| Andarine(S4) | partial agonist, intended mainly for treatment of benign prostatic hypertrophy |
| SR9009 | under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice |
| RAD140 | New generation for gaining mass and cutting edges |
| YK11 |
a SARM and myostatin inhibitor in one
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Function
AICAR strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK, and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).
AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase. AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathway
FAQ
Q1: Have your Product Quality been Approved by Third Party Lab
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2. Are you a manufacturer?
A: Yes, we have our own factory and lab.
Q3: Is there any discount?
A: Yes, as for old customers and larger quantity, we always support with great discounts and surprise.
Q4:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card, we'd like to accept Western Union, MoneyGram, Bank Transfer, Bitcoin, Litecoin.
Q5: How do you treat quality complaint?
A: First of all, our QC department will do strict examination of our export products in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6: How to proceed order?
1st: Please let me know what you need-Which product/Cas No. quantity, and the destination country.
2nd: You send us the purchase order once we come to an agreement on all details.
3rd: Parcel would be delivered upon full payment received.
4th: Express Tracking No.will be provided about the parcels.
5th: You will get the parcels within 7days.
6th: After-sales service would be provided after you receive parcels.
Muscle Building SARM Raw Powder 99% High Purity AICAR Powder ACADESINE Powder CAS: 2627-69-2
Enter Your Message
| Shaanxi Jingyuan Biotechnology Co., Ltd. |
| B2406, Chuangye Square, Keji Road, High-tech Zone, Xi'an, Shaanxi, China |
| 86-029-62397510 |
| 3231631479@qq.com |
