China SARMs Liquid manufacturer

99.8% Purity Pharmaceutical Aicar SARMs For Bodybuilding

Product Details:
Place of Origin: shaanxi
Brand Name: xn
Certification: GMP,SGS,BV,ISO
Model Number: aicar
Payment & Shipping Terms:
Minimum Order Quantity: 1g
Price: Negotiable
Packaging Details: Aluminum foil bag, carton or more according to customer requirements
Delivery Time: Within 24 hours after payment
Payment Terms: T/T, Western Union, MoneyGram,bitcoin
Supply Ability: 3000kg/month

Detail Information

Name: Aicar Cas: 2627-69-2
Purity: 99.5% MW: 624.776
Molecular Formula: C27H36N4O5S.CH4O3S Usage: Bodybuilding&athletes Competition
Character: White Powder Place Of Origin: China
High Light:

Pharmaceutical Aicar SARMs

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99.8 percent Purity Acadesine powder

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Aicar SARMs Bodybuilding

Product Description

SARMs Steroids AICAR 99.8% Purity Pharmaceutical Raw Material Acadesine CAS 2627-69-2 For Bodybuilding

 

AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac
cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

Commerce Clause

Minimum Order Quantity: 1g
Price: Negotiable
Payment Terms: Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin
Packaging Details: Discreet and Disguised packing
Delivery time: Within 24 hours after receiving the payment
Leading time: 4~6 working days after confirming the payment
Delivery By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door)bulk order can be negotiable
Tracking number can be offered to you within 24h
Supply Ability: Mass in stock

2. History:

 

AICAR has been used medically to help with restriction of blood supply to tissues, called ischemia. Interestingly, in the 1980’s it was sometimes used during surgery to help preserve blood flow to the heart. These days, AICAR shows to be promising in diabetes treatment because of its ability to increase metabolic activity of tissues by changing the composition of muscles in the body.

 

99.8% Purity Pharmaceutical Aicar SARMs For Bodybuilding 0

 

Related SARMs and Usage:

name Usage
AICAR acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown
MK2866 medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy.
MK-677 A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly
LGD-4033 pharmacological profile similar to that of enobosarm, Ostarine,MK-2866
GW1516 For obesity, diabetes, dyslipidemia and cardiovascular disease
Andarine(S4) partial agonist, intended mainly for treatment of benign prostatic hypertrophy
SR9009 under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice
RAD140 New generation for gaining mass and cutting edges
YK11

a SARM and myostatin inhibitor in one

 

99.8% Purity Pharmaceutical Aicar SARMs For Bodybuilding 1

3. Description:

 

AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

 

4. Function:

 

AICAR strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK, and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

 

AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.

 

99.8% Purity Pharmaceutical Aicar SARMs For Bodybuilding 2

SARMs Steroids AICAR 99.8% Purity Pharmaceutical Raw Material Acadesine CAS 2627-69-2 For Bodybuilding

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