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Product Details:
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| Place of Origin: | shaanxi |
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| Brand Name: | xn |
| Certification: | GMP,SGS,BV,ISO |
| Model Number: | aicar |
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Payment & Shipping Terms:
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| Minimum Order Quantity: | 1g |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag, carton or more according to customer requirements |
| Delivery Time: | Within 24 hours after payment |
| Payment Terms: | T/T, Western Union, MoneyGram,bitcoin |
| Supply Ability: | 3000kg/month |
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Detail Information |
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| Name: | Aicar | Cas: | 2627-69-2 |
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| Molecular Formula: | C27H36N4O5S.CH4O3S | Character: | White Powder |
| Purity: | 99.5% | Usage: | Bodybuilding&athletes Competition |
| MW: | 624.776 | Place Of Origin: | China |
| High Light: | Pharmaceutical steroid hormones bodybuilding,steroid hormones bodybuilding ISO,Aicar CAS 2627-69-2 |
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Product Description
Aicar Sarm Pharmaceutical Raw Materials , Steroid Hormones Bodybuilding CAS 2627-69-2
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.
Commerce Clause
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Product Description:
AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.
It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac
cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Related SARMs and Usage:
| name | Usage |
| AICAR | acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown |
| MK2866 | medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy. |
| MK-677 | A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly |
| LGD-4033 | pharmacological profile similar to that of enobosarm, Ostarine,MK-2866 |
| GW1516 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
| Andarine(S4) | partial agonist, intended mainly for treatment of benign prostatic hypertrophy |
| SR9009 | under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice |
| RAD140 | New generation for gaining mass and cutting edges |
| YK11 |
a SARM and myostatin inhibitor in one
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Function:
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Packaging & Service:
1. Keep a large amount of stock to ensure timely delivery after daily payment.
2. We have been engaged in this field for many years, with excellent professional logistics department, which can ensure safe and fast delivery.
3. The well-trained and well disciplined packaging team is specialized in providing you with safe packaging. At the same time, it also avoids the occurrence of many emergencies and ensures the high pass rate. A unique way to deliver 10 g to 20 kg of powder (or 100 ml to 30 l of liquid) at a time to the destination.
4. Provide package picture and pin number within 24 hours after receiving payment for goods. Updated tracking code will be provided every other day just so you can hold your package palm.
5. Perfect after-sales service: any questions or problems after receiving the product. Please feel free to contact us. All day online to solve your problems!
Aicar Sarm Pharmaceutical Raw Materials , Steroid Hormones Bodybuilding CAS 2627-69-2
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| Shaanxi Jingyuan Biotechnology Co., Ltd. |
| B2406, Chuangye Square, Keji Road, High-tech Zone, Xi'an, Shaanxi, China |
| 86-029-62397510 |
| 3231631479@qq.com |
