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Product Details:
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| Place of Origin: | shaanxi |
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| Brand Name: | xn |
| Certification: | GMP,SGS,BV,ISO |
| Model Number: | aicar |
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Payment & Shipping Terms:
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| Minimum Order Quantity: | 1g |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag, carton or more according to customer requirements |
| Delivery Time: | Within 24 hours after payment |
| Payment Terms: | T/T, Western Union, MoneyGram,bitcoin |
| Supply Ability: | 3000kg/month |
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Detail Information |
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| Name: | Aicar | Cas: | 2627-69-2 |
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| Molecular Formula: | C27H36N4O5S.CH4O3S | Character: | White Powder |
| Purity: | 99.5% | Usage: | Bodybuilding&athletes Competition |
| MW: | 624.776 | Place Of Origin: | China |
| High Light: | Aicar SARMs Powder,aicar 50mg Per Vial,Raw Aicar SARMs |
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Product Description
Raw Powder Aicar Sarm Powder AICAR 50mg Per Vial Crystalline Solid Formulation
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
Description
AICAR is a cell-permeable adenosine analog that is a selective activator of AMP-activated protein kinase (AMPK) in adipocytes and hepatocytes. The AMPK is a metabolic regulator that inhibits anabolic processes and is active when energy availability is reduced. AICAR is reported to promote osteogenic differentiation of mesenchymal stem cells in vitro and astroglial differentiation in neural stem cells.
Commerce Clause
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CAS Number
2627-69-2
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:
Sullivan, J. E., Brocklehurst, K. J., Marley, A. E., Carey, F., Carling, D., & Beri, R. K. (1994). Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS letters, 353(1), 33-36.
Young, M. E., Radda, G. K., & Leighton, B.
(1996). Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR—an activator of AMP-activated protein kinase. FEBS letters, 382(1), 43-47.
Iglesias, M. A., Ye, J. M., Frangioudakis, G., Saha, A. K., Tomas, E., Ruderman, N. B., ... & Kraegen, E. W. (2002). AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats. Diabetes, 51(10), 2886-2894
Related SARMs and Usage:
| name | Usage |
| AICAR | acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown |
| MK2866 | medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy. |
| MK-677 | A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly |
| LGD-4033 | pharmacological profile similar to that of enobosarm, Ostarine,MK-2866 |
| GW1516 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
| Andarine(S4) | partial agonist, intended mainly for treatment of benign prostatic hypertrophy |
| SR9009 | under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice |
| RAD140 | New generation for gaining mass and cutting edges |
| YK11 |
a SARM and myostatin inhibitor in one
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Dosage
Dosages range from 150 milligrams (mg) per day (if stacked with GW), up to 500mg a day when used solo. Considering the fact that each bottle typically comes in 50mg dosages, that is quite expensive, as already mentioned above. Economically, it makes most sense to run AICAR during the 4 weeks leading up to your competition.
Business details
1. We use HKEMS,EMS, Fedex, EUB and so on to deliver the goods, the clearance rate is very high and it’s safe, fast.
2. Our payment option: Western Union, Money Gram, TT, Bitcoin
3. The Min.order is 50g of each item, but for some highly valued products and be adjusted appropriately.
4. The packing will not contain any hormone information and be marked with other common chemical names, so that it can go through the custom smoothly.
5. We also offer the complete reshipping policy for our clients if any order seized.
6. High quality, reasonable price, first-class service, high successful delivery rate can be offered.
7. we can delivery quickly at the very day when receive the payment for we have enough goods in stock.
Packaging & Service:
1. Keep a large amount of stock to ensure timely delivery after daily payment.
2. We have been engaged in this field for many years, with excellent professional logistics department, which can ensure safe and fast delivery.
3. The well-trained and well disciplined packaging team is specialized in providing you with safe packaging. At the same time, it also avoids the occurrence of many emergencies and ensures the high pass rate. A unique way to deliver 10 g to 20 kg of powder (or 100 ml to 30 l of liquid) at a time to the destination.
4. Provide package picture and pin number within 24 hours after receiving payment for goods. Updated tracking code will be provided every other day just so you can hold your package palm.
5. Perfect after-sales service: any questions or problems after receiving the product. Please feel free to contact us. All day online to solve your problems!
Raw Powder Aicar Sarm Powder AICAR 50mg Per Vial Crystalline Solid Formulation
Enter Your Message
| Shaanxi Jingyuan Biotechnology Co., Ltd. |
| B2406, Chuangye Square, Keji Road, High-tech Zone, Xi'an, Shaanxi, China |
| 86-029-62397510 |
| 3231631479@qq.com |
